Blue Sky is the industry’s premier protein expression CRO. Blue Sky is proud to offer our clients a diverse range of tissue culture and fermentation services. Our team will develop protocols through multiparallel small-scale protein expression studies and scale protein expression in bioreactor systems.

Research-scale bioreactor (10-60L) expression in bacterial systems (E. coli) is typically completed in less than 7 business days. Scale-Up fermentation of yeast in 10-60L bioreactors is also very fast- less than 10 business days!

Blue Sky is widely recognized for its pioneering technologies and leadership in baculovirus production, baculovirus amplification, and bioreactor-scale protein expression. The Insect Expression Team has invested > 2Million USD in technology improvements of the baculovirus production and expression process. Blue Sky’s industry-leading baculoviral [insect cell recombinant protein expression] service utilizes Infection Kinetics Monitoring® [IKM], a proprietary process technology that significantly improves turnaround time and reproducibility in tandem with TIPS/BIIC technology. 100L Turnaround Time in < 12 business days!

Research-based drug discovery increasingly relies on protein/antibody production using mammalian host cell lines. In particular demand has grown for fast turnaround bulkscale mammalian suspension cell expression. Blue Sky offers its clients distinctly efficient research-scale (up to 200L) mammalian cell expression services.